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Exploring The Best NAD+ Supplements for Optimal Health

Written by Jinfiniti Email on . Posted in Aging, Exercise and Fitness, NAD & NAD Precursors.

Maintaining optimal health is a goal that many individuals strive to achieve. To support this goal, numerous supplements have emerged in the market, with one of the most promising being NAD+ supplements.

In this article, we talk about…

  • The powerful health benefits of NAD+ and its secret connection to aging gracefully.
  • The variety of NAD plus supplements on the market and discover which one might be your personal fountain of youth.
  • Potential side effects of NAD+ and how to mitigate them for a safe and effective supplementation experience.

Boost your NAD+ levels to optimize your health and longevity. Get an exclusive 20% OFF today by using code Blog20. Click here to order.

Understanding NAD+ Benefits on Health

NAD levels naturally decline as you age, leading to reduced cellular function and an increased susceptibility to age-related diseases. Supplementing with NAD+ is believed to enhance your health and potentially slow aging.

Energy metabolism is a fundamental process in the body that allows you to convert the food you consume into usable energy. NAD is a key player in this process as it acts as a coenzyme in the reactions that occur during energy production.

Without sufficient NAD+ levels, the cells may struggle to produce energy efficiently, leading to fatigue and a decreased ability to perform daily activities.

In addition to its role in energy metabolism, NAD+ is also involved in DNA repair.

Your DNA is constantly exposed to various damaging agents, such as radiation and toxins, which can cause DNA mutations. NAD helps to repair these DNA damages, ensuring the integrity of your genetic material.

Without adequate NAD levels, your cells may struggle to repair DNA efficiently, potentially leading to the accumulation of mutations and an increased risk of developing diseases, including cancer.

Besides its direct involvement in energy metabolism and DNA repair, NAD also plays a crucial role in maintaining overall cellular health.

It is involved in regulating various cellular processes, including cell signaling and gene expression.

NAD acts as a signaling molecule, communicating information between different cellular components and coordinating their activities. This communication network is essential for maintaining cellular homeostasis and ensuring your cells function optimally.

Reduced NAD plus levels may also lead to a decline in cellular function, making your cells more susceptible to damage and less efficient at carrying out their vital tasks. This decline in cellular function can contribute to the development of age-related diseases, such as neurodegenerative disorders and cardiovascular conditions.

However, researchers have discovered that taking NAD+ supplements can potentially reverse some of the age-related cellular decline.

By boosting NAD plus levels, you can enhance cellular function, improve energy production, and promote overall health and longevity.

Studies have shown promising results, suggesting that NAD supplementation may have beneficial effects on various aspects of health, including cognitive function, cardiovascular health, and metabolic function.

In conclusion, NAD+ is a vital coenzyme that plays a crucial role in cellular health.

Its involvement in energy metabolism, DNA repair, and overall cellular function highlights its importance in maintaining optimal health.

The Connection Between NAD+ and Aging

NAD Levels and Aging Process

Research suggests that declining NAD levels contribute to the aging process and may pose harm to various biological processes.

When NAD+ levels decrease, DNA repair mechanisms become less efficient, leading to an accumulation of DNA damage.

This accumulation can result in the development of age-related conditions such as cancer, neurodegenerative diseases, and cardiovascular disorders. Additionally, reduced NAD levels can impair energy production in our cells, leading to decreased metabolic activity and an overall decline in physiological functions.

ALT TXT IMG: Supplements

Replenishing and Boosting NAD+ Levels

Recognizing the importance of NAD in maintaining cellular health, scientists have been exploring ways to boost NAD levels and potentially slow down the aging process.

One approach is through NAD+ supplementation, which involves providing the body with external sources of NAD+ precursors.

Studies have shown that NAD supplements can increase NAD+ levels in various tissues and organs, including the brain, heart, and skeletal muscles.

By restoring NAD levels, you may be able to support DNA repair mechanisms, enhance energy production, and improve overall cellular function. This, in turn, could potentially delay the onset of age-related conditions and promote healthy aging.

Reversing Aging: The Role of NAD+

In addition to its potential preventive effects, NAD plus supplementation has also shown promise in reversing certain aspects of aging. Animal studies have demonstrated that increasing NAD levels can improve mitochondrial function, the powerhouses of our cells responsible for energy production.

Enhanced mitochondrial function can lead to increased energy production, improved cellular metabolism, and reduced oxidative stress. These changes can have a profound impact on overall healthspan, the period of life spent in good health, by delaying the onset of age-related decline and promoting longevity.

Furthermore, research has suggested that NAD supplementation may have cognitive benefits, such as improved memory and learning abilities. By supporting brain health and function, NAD could potentially help combat age-related cognitive decline and neurodegenerative diseases.

While the research on NAD and its role in aging is still evolving, the potential benefits of maintaining optimal NAD levels are promising. As scientists continue to unravel the intricate mechanisms underlying the aging process, NAD supplementation remains an intriguing avenue for further exploration in the quest for healthy aging.

Different Types of NAD Supplements

NAD+ Supplements 

NAD+ supplements directly provide the NAD+ molecule, allowing for immediate utilization by the body. However, the NAD+ molecule is too big and unstable and the NAD+ is usually not delivered by oral supplements. NAD+ is usually delivered through NAD+ IV therapy, which does not increase intracellular NAD levels, or via NAD injections that only moderately increase NAD+ levels inside the cells.

NAD+ precursor Supplements

NAD+ precursor is converted into NAD in the body. NAD+ precursor supplements aim to boost NAD levels by providing the building blocks necessary for NAD synthesis.

NR Supplements

NR (Nicotinamide Riboside) is another precursor to NAD. Like NAD+ precursor, NR supplements also aim to increase NAD levels by providing a precursor molecule that can be easily converted into NAD within the body.

NAD+ supplements are among the most popular choices for individuals looking to replenish their NAD levels efficiently.

By providing the precursors of the NAD molecule, these supplements offer immediate absorption and utilization by the body. This means that the NAD molecule is readily available for the body to use, supporting various cellular functions and promoting overall vitality.

NAD+ Precursor

NAD+ precursor is converted into NAD in the body through a series of enzymatic reactions.

By taking NAD+ precursor supplements, people aim to boost their NAD levels by providing the building blocks necessary for NAD synthesis. This can help support cellular energy production, DNA repair, and other vital processes that rely on NAD.

Similarly, NR supplements, which stands for Nicotinamide Riboside, also aim to increase NAD levels in the body. Like NAD+ precursor, NR is a precursor molecule that can be easily converted into NAD within the body.

By supplementing with NR, individuals provide their cells with the necessary raw materials to support NAD synthesis. This can have a positive impact on various aspects of health, including metabolism, cellular repair, and overall well-being.

It’s important to note that while NAD_ supplements offer promising benefits, they should be used as part of a comprehensive approach to health and wellness.

A balanced diet, regular exercise, and a healthy lifestyle are all crucial factors in maintaining optimal NAD levels and overall well-being. Consulting with a healthcare professional is also recommended before starting any new supplement regimen to ensure it aligns with individual health goals and needs.

In conclusion, NAD supplements, including NAD, NAD+ precursor, and NR, provide different approaches to support and optimize NAD levels in the body.

Whether it’s through direct NAD supplementation or providing precursor molecules for NAD synthesis, these supplements offer potential benefits for cellular health, energy production, and overall vitality. However, it’s important to approach NAD supplementation as part of a holistic approach to health and wellness, incorporating other lifestyle factors that contribute to overall well-being.

Choosing the Best NAD+ Supplement 2024

Factors to Consider When Choosing NAD Supplements

When selecting an NAD supplement, it is important to consider factors such as quality, dosage form, dosage strength, and reputation of the manufacturer. It is advisable to consult with a healthcare professional to determine the most suitable NAD supplement for your specific needs.

The Bioavailability of NAD Supplements

Bioavailability refers to the amount of a substance that is effectively absorbed and utilized by the body. Not all NAD supplements have the same bioavailability. It is crucial to choose a supplement that has high bioavailability to ensure maximum efficacy.

The Potential Side Effects of NAD Supplements

Common Side Effects

While NAD supplements are generally well-tolerated, some individuals may experience mild side effects such as nausea, dizziness, or gastrointestinal discomfort. These side effects are usually temporary and subside as the body adjusts to the supplement.

Precautions and Contraindications

It is important to note that individuals with certain medical conditions or those taking specific medications may need to exercise caution when using NAD supplements. It is always advisable to consult with a healthcare professional before starting any new supplement regimen.

Conclusion

In conclusion, NAD+ supplements offer a promising avenue for promoting optimal health and potentially slowing down the aging process.

By understanding the biological importance of NAD plus, its connection to aging, the different types of NAD supplements available, and the factors to consider when choosing the right NAD supplement, individuals can make informed decisions about their health and well-being.

It is important to prioritize safety and consult with healthcare professionals to ensure the best possible outcomes. Remember, making informed choices in supplementing with quality NAD supplements like Vitality Boost can be an important step to optimal health.

Lastly, if you’re interested in going deeper on health-related content, here are a few of our recent posts that you may want to read:

  1. Why Optimized, Precision Medicine is the Future
  2. Andrew Huberman is Wrong About NAD, NAD+ precursor & Longevity
  3. 9 Powerful Benefits of Optimizing Your NAD
  4. What Does Peak Performance Look Like? 

P.S. Want to boost your intracellular NAD levels? Try a 2 week trial of our Jinfiniti Vitality Boost (do 2 scoops per day), use the discount code Blog15 if you’re a new customer for 15% off your 1st order)

Boost your NAD levels to optimize your health and longevity. Get an exclusive 20% OFF today by using code Blog20. Click here to order.

Andrew Huberman is Wrong About NAD+, NR, and Longevity

Written by Jinfiniti Email on . Posted in Aging, NAD & NAD Precursors.

Recently, Stanford neuroscientist Dr. Andrew Huberman (who has one of the top health podcasts in the world) did a 16-minute Q&A segment on NAD and its precursors. 

Overall, I respect his commitment to scientific accuracy and his standard of excellence with his approach.

However, I consider him under-informed and not a subject matter expert in this particular arena.

Here’s where Huberman is wrong about NAD+, NR, and longevity.

In this article, you’ll discover…

  • Why you should not trust Andrew Huberman’s opinion about NAD supplements and why his expertise may not fully cover the complexities of NAD research, potentially leading to overestimated benefits.
  • Discover why NAD IV treatments might not be as effective as Andrew Huberman suggests and how they could be draining your wallet without delivering the promised health benefits.
  • The only NAD supplement proven to boost levels by 200-300%, far exceeding the modest 20-40% increase seen with other NAD products.

Boost your NAD levels to optimize your health and longevity. Get an exclusive 20% OFF today by using code Blog20. Click here to order.

Let’s start with where we agree with Dr. Huberman:

  1. NAD provides a noticeable increase in energy: Dr. Huberman takes NAD+ precursor daily because of the very noticeable improvement in energy. In his words, “It gives me a lot of sustainable physical and mental energy throughout the day. I noticed a decrease in energy when I stopped taking NAD+ precursor. While I wasn’t totally depleted, my energy was noticeably lower. As a 48-year-old, having great energy is important to me.”
  2. We need more data and research. There are countless studies, tens of millions of dollars and many different types of clinical trials underway and completed. But because NAD shows enormous promise and potential, we can’t do enough research fast enough. Plus, it takes years for many trials and studies to be completed. 

However, there are a few important points where I disagree with Dr. Huberman. I believe he is seeing an incomplete picture with regards to NAD and its role in so many of our body’s systems. 

Here’s where we disagree: 

  1. Optimal Levels of NAD Increase Lifespan by Increasing Healthspan: While there haven’t been conclusive studies done on humans to demonstrate that NAD extends lifespan, you’d be hard-pressed to find any conclusive clinical trials and studies on any molecule or nutrient that slows aging.  Furthermore, the six root causes of aging that are central to long term health are all influenced, if not directly affected, by NAD. If your NAD levels are deficient, your metabolic function suffers significantly, which we know intensifies and accelerates your aging as well as your likelihood of disease. 
  1. Supplements are fundamental to optimal health: He claims that supplements are NOT fundamental to life/health, which is obviously wrong. Most of us are deficient in multiple nutrients for one reason or another and supplementation is an invaluable way to boost and support our health, improving our healthspan and thereby extending our lifespan.
  1. NAD+ precursor clearly elevates NAD levels (especially Vitality Boost): Huberman says he does not know if NAD+ precursor can elevate NAD.  He is ignoring all the publications and consumer data that NAD+ precursor can elevate NAD and the functional/clinical benefits. His statement is contradictory to his own experience that it gives him more energy with cellular energy being a fundamental aspect of good health. We see thousands of test results every year that conclusively demonstrate that your intracellular levels can be substantially increased, especially with our Vitality Boost, of which no other supplement comes close to increasing NAD levels as effectively.
  1. NAD IV. There’s much that we don’t know about the effectiveness of intravenous NAD, but one thing we do know is that it has no measurable impact on raising the NAD levels in your blood. Within hours of getting an IV, your system has flushed out the NAD from your bloodstream. Huberman seems to believe that your NAD levels increase with NAD IV, which is not the case at least intracellularly though they do seem to increase in your plasma. Here’s a feature that RaisingNAD.com did on me where we discussed the research that indicates no perceptible impact to intracellular NAD though your cellular plasma NAD levels do seem to increase.

See our YouTube video this week comparing NAD IV vs. Vitality Boost.

Many people do notice an increase in energy and reduction in anxiety for a time period ranging from several days to several weeks after an IV, and we also agree that NAD IVs are a very expensive (and even painful) way to increase NAD. 

Dr. Huberman deserves a thumbs-up for his overall approach and standard of scientific rigor. As a fellow scientist, I have served as a Division Chief of Experimental Pathology and Director of Research and was the founding Director for Biotechnology and Genomic Medicine, as well as the director of two core research facilities in Genomics, Proteomics, and Mass Spectrometry.

As a genetics researcher for over 40+ years, I have reviewed thousands of intracellular NAD tests, authored over 400-peer reviewed papers with an H-index of 76 and over 20,000 citations, and secured over $100 million dollars in research grants. . 

Here at Jinfiniti, our flagship NAD supplement, the Accuri® Vitality Boost, is a patent-pending formulation that has been extensively tested in clinical studies by hundreds of clinics and by thousands of consumers. It allows optimization of NAD in approximately 90% of users, a figure incomparable to any other NAD supplementation on the market. 

I strongly disagree with both Dr. Andrew Huberman’s assessment of NAD and its precursors. His understanding of NAD and its precursors is far less than what’s currently available. He hasn’t had the privilege of thousands of intracellular NAD tests. 

As someone who has a deep and integral knowledge of NAD and its precursors, I have a much more expansive data set and perspective when it comes to NAD and its role in our health. It is my primary area of focus. 

With regards to neuroscience, Huberman is the expert. But as far as genetics and NAD are concerned, that’s my field of expertise. 

Vitality Boost optimizes—not just improves—intracellular NAD for 90% of people alone, which no other NAD supplement can come close to promising.

While other brands increase NAD levels by 20-40% at best, we often see levels increase by 200-300% as we did with Doc Jen, a prominent doctor of physical therapy who loves the Vitality Boost. We back it with a 60-Day Money-Back and Efficacy Guarantee. That’s because we back up our Vitality Boost with testing, where all of the proof lies! 

I highly recommend testing your NAD levels to see where your levels are at and how much they need to be optimized. Jinfiniti’s intracellular NAD test is the only one of its kind in the world, and if you don’t already know where your levels are, it’s the best place to begin your optimization journey. 

Here are a few of our recent blog posts that you may be interested in reading regarding some of the science behind NAD, NAD precursors, and optimization leading to longevity: 

Lastly, as much as we know about NAD and its role in our health, there’s substantially more to be discovered, so I consider us very much in the early days of figuring out how to extend our lifespan. From the research and the experiential evidence I see every week with countless customers, NAD plays a vital role in extending our health span, life quality, and cellular vitality.

Lastly, if you’re interested in going deeper on health-related content, here are a few of our recent posts that you may want to read:

  1. 9 Powerful Benefits of Optimizing Your NAD
  2. Why Optimized, Precision Medicine is the Future
  3. Andrew Huberman is Wrong About NAD & Longevity
  4. What Does Peak Performance Look Like? 

Boost your NAD levels to optimize your health and longevity. Get an exclusive 20% OFF today by using code Blog20. Click here to order.

Research indicates that cellular senescence can be reduced with lifestyle changes and micronutrient optimization like NAD

Everything You Need to Know About NAD and its Precursors: NR and N-M-N

Written by Jinfiniti Email on . Posted in Aging, NAD & NAD Precursors.

Let’s talk about NAD+ precursors. What are they? 

NAD precursors are the very things that your body uses to create its own NAD. 

Out of all the NAD precursors that exist, the most efficient precursors (ones that take the least amount of energy to convert to NAD) only takes one enzymatic step or two enzymatic steps (NR).

(And in case you need a refresher, nicotinamide adenine dinucleotide or NAD is a crucial coenzyme found in every cell of the body, playing a central role in various biological processes, including energy production, DNA repair, and regulation of gene expression.)

As we age, NAD levels tend to decline, which has been linked to various age-related diseases and a decrease in overall vitality.

NAD+ precursor is a molecule composed of a nicotinamide group and a ribose molecule, making it an intermediate in the NAD biosynthetic pathway. When NAD+ precursor is consumed, it can be efficiently converted into NAD in the body, making it a popular choice for NAD supplementation.

But on the other hand, NR, or nicotinamide riboside, is another NAD precursor that has gained prominence. NR is a form of vitamin B3 that can be converted into NAD through a two-step enzymatic process. NR supplementation has shown promise in increasing NAD levels in various preclinical and clinical studies, making it another valuable precursor for those seeking to support their cellular NAD health.

Both of these precursors have been shown to effectively increase NAD+ levels in the body when taken in supplement form. So, which one should you take, and why?

It turns out the answer may be: both. 

The use of both NAD+ precursors can be beneficial because they complement each other in the NAD biosynthesis pathway. 

While one step NAD+ precursor provides a more direct route to NAD+ production, NR can serve as an indirect source by being converted to NAD+ precursor. This redundancy helps maintain NAD levels and allows the body to adapt to varying conditions, ensuring a steady supply of this crucial coenzyme for various cellular processes. 

So while NAD+ precursor and NR are both effective precursors to your body’s ability to create its own NAD, different tissues and organs (as well as different microbiomes) may prefer one precursor over the other. 

That’s why here at Jinfiniti, our patent formula helps your body create both in our Vitality Boost. And, in fact, we’re the only company to do this in the world. 

So no matter which type of precursor suits you best, your body is able to create the cellular fuel—the NAD—your body needs. 

In summary: 

  • NAD+ precursor and NR are both precursors to NAD.
  • Both precursors safely and effectively increase NAD levels when taken as a supplement.
  • Different tissues and organs (and different microbiomes) may prefer one precursor over the other.
  • Jinfiniti’s Vitality Boost is the only NAD product in the world that helps your body activate both precursors, NAD+ precursor and NR. 

The noted biohacker, expert Bryan Johnson, uses our product and has featured Jinfiniti in many of his Instagram posts. One of the most recognized authorities in the biohacking space, he has turned back his aging almost ten years and is a huge fan of Jinfiniti. Johnson recommends both our tests and our Vitality Boost. 

Our formula also optimizes—not just improves—intracellular NAD for 90% of people alone, which no other NAD supplement can come close to promising.

And that’s why we confidently back it with a 60-day Money Back and Efficacy Guarantee.

Lastly, if you’re interested in going deeper on health-related content, here are a few of our recent posts that you may want to read:

  1. What Does Peak Performance Look Like? 
  2. 9 Powerful Benefits of Optimizing Your NAD
  3. Andrew Huberman is Wrong About NAD, NAD+ precursor & Longevity
  4. Why Optimized, Precision Medicine is the Future

P.S. Want to boost your intracellular NAD levels? Try a 2 week trial of our Jinfiniti Vitality Boost (do 2 scoops per day), use the discount code Blog15 if you’re a new customer for 15% off your 1st order).